Canonical Wnts function as potent regulators of osteogenesis by human mesenchymal stem cells
نویسندگان
چکیده
منابع مشابه
Canonical Wnts function as potent regulators of osteogenesis by human mesenchymal stem cells
Genetic evidence indicates that Wnt signaling is critically involved in bone homeostasis. In this study, we investigated the functions of canonical Wnts on differentiation of adult multipotent human mesenchymal stem cells (hMSCs) in vitro and in vivo. We observe differential sensitivities of hMSCs to Wnt inhibition of osteogenesis versus adipogenesis, which favors osteoblastic commitment under ...
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ژورنال
عنوان ژورنال: Journal of Cell Biology
سال: 2009
ISSN: 1540-8140,0021-9525
DOI: 10.1083/jcb.200810137